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Sunday, March 21, 2010

Hormonal Balance Requires Avoiding Common Pitfalls

Are you having a hormonal problem despite pills , vitamins and herbal remedies ?

Many people suffer chronic health imbalances and mental meltdowns due to too much or too little hormones and we want to guide you out of the jungle.

Many hormone and common complaints like fatigue and irritability are due to
low blood sugar. This condition can lead to adrenal exhaustion and pregnenolone steal(see my previous blog -DHEA Need = Adrenal Stress Disorder).

Insulin can be over produced due to low blood sugar as well as from high blood sugar. The insulin can lead to what is now known as insulin resistance. The most common way to locate this by symptoms is being tired after a meal or craving sugar (dessert)or coffee after eating(or a nap).

Low Blood Sugar is probably the most common cause of Female hormone imbalances and if not corrected soon enough may lead to increasing the potential for women to convert Estrogen to Testosterone (the #1 most common Hormone imbalance in women).
This in turn may lead to polycytic ovarian syndrome know as PCOS, as well as elevated Estorgen, elevated LH, elevated Androstendione, elevated DHEA and decrease in Sex-Hormone Binding Globulin(protein).

The above hormones all hinge on proper blood sugar and so does your production of Neurotransmitters like : Serotonin, Dopamine, AcetylCholine and the primary one that makes you relax, GABA (gam·ma-a·mi·no·bu·tyr·ic acid).

Adrenal and Blood Sugar Balance are vital to achieve Hormonal Balance.

Once the cause are revealed the problem can begin to be properly supported. Overly Simple and short term solutions do not give long term correction in most cases.

To achieve balance in the hormones there are 5 vital building blocks which must be repaired when needed.

The 5 primary barriers to repairing hormones are:

1. Low Adrenal function - check with StressCheck

Metabolic Assessment Form

To WIN the Hormone Balance Game -The above is the most important to begin with!

2. Check your Glucose ( blood sugar ) level on a Morning fasting ( 12 hours no food - only water) Blood Test.

The next barrier to over come would be elimination of Inconsistencies taking vitamins (not taking them 2-3x daily) and not making lifestyle changes long enough to re-balance the system.

Other Barriers are :Allergies and infections(See Blood Test) . -High Eosinophils (over 3) and High WBC’s-(White Blood Cells-over 8 or under 5 with chronic infection)
Lack of Essential Fatty acids (See Blood Test -Triglycerides less than ½ total Cholesterol value) .

Liver and Gallbladder dysfunctions (See Blood Test-ALT and or AST above 26 . and check with Metabolic Assessment Form


Progesterone has many effects on healthy brain function including activating the major cells and nerve signaling. It can also stimulate the growth of nerve cells which create myelin sheath for brain insulation. Progesterone can activate the GABA receptors in the brain which creates a calming effect. We have GABA-Pro as a supplement which can also improve this.

The Progesterone hormone is important in the regulation of stress, post partum depression, memory, cognition, PMS, depression and other functions. Progesterone receptors in the brain are controlled by dopamine.

Studies show that Progesterone is also very powerful in protecting brain tissue (also called neuro-protective) as well as having an anti-inflammatory effect. Progesterone has demonstrated speeding the recovery of the brain after trauma.

As with any hormone, too much Progesterone or not enough are both problems. When hormone creams are used they tend to have adverse effects. Hormones can be stored in the fat and this can cause imbalances. Excess Progesterone can overload the receptors and the person may develop symptoms of low Progesterone - even though the opposite is true. The response of hormones is lost also due the Pituitary gland in the brain not releasing its hormones when it senses too much present.


1. The enzyme that converts Cholesterol into Pregnenolone is very limited and this conversion is a difficult step for the human body. There is only so much Pregnenolone produced each day, so if the conversion toward Progesterone as seen in Adrenal Stress is over-active, DHEA and sex hormone production will suffer.
2. This enzyme is elevated by too much insulin; unfortunately the enzyme that converts Androstenedione to Estrone is also elevated. The net effect is the conversion of Pregnenelone into DHEA and Androstenedione followed by immediate conversion of DHEA into Esterone. Non optimal for men.
3. DHEA is converted into Androstenedione by the same enzyme used in reversing the conversion of Androstenedione into Testosterone and reversibly converting Esterone into Estrodial. It's common to see high levels of Androstenedione when this enzyme is high. It is also common to experience symptoms of low sex hormones due to high levels of this enzyme. This is because the receptors to sex hormones lose their sensitivity. This shows up clinically as a person with symptoms of low sex hormones.
4. Taking oral Pregnenolone stimulates the conversion into Progesterone in healthy males. However the potential for oral Pregnenolone conversion into any other hormone is possible especially in men that have insulin resistance and too much Estrogen production.
5. When the conversion of Progesterone to Aldesterone is overactive the culprit is frequently high Cortisol. Cortisol appears to have a high affinity for Aldosterone receptor sites and can bind to them creating an Aldosterone response. Symptoms such as high blood pressure and electrolyte imbalance when there are no changes in blood or urine Aldosterone indicate an elevation in Cortisol. This syndrome is known as "pseudohyperaldosteronemia".
6. Conversion of Progesterone to Androstenedione takes place with adrenal stress or insulin resistance. Ideally Progesterone should convert into Cortisol instead.
7. When a person has a chronic stress response, giving Progesterone will usually elevate Cortisol. Therefore, any doctor should be wary of the conversion of Progesterone into excess Cortisol. He must be cautious even with patients who demonstrate low Progesterone and low Cortisol. Many times even a small amount of Progesterone will cause a "jump" immediately into a high Cortisol pattern. The person will experience all the side effects of high Cortisol, such as weight gain, inability to fall asleep (insomnia), insulin resistance, etc.
8. The majority of Testosterone creation is determined by the production and secretion of Luteinizing Hormone (LH) by the Pituitary gland. This can be supported in men using Opticrine.
9. The enzyme responsible for converting Testosterone to Dihydrotestosterone appears to increase with low Progesterone levels, Essential Fatty Acid deficiency, and Zinc deficiency.
10. Conversion of Testosterone and Androstenedione to Estradiol and Esterone is controlled by an enzyme found in fatty tissues. This enzyme called aromatase increases as Cortisol and Insulin levels increase. When overactive it can be blocked by using the Testanex Cream rubbed into the belly adipose (fatty tissue).

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