K-35 Ultra-D Complex
BENEFITS OF PRODUCT
Ultra-D Complex™ is an advanced vitamin D formula. It contains a concentrated 2,000 IU serving of vitamin D in a natural base of cod liver oil without an offensive fishy taste. The use of natural cod liver oils is believed to provide natural sources of vitamins D, A, and K, as well as EPA and DHA that are necessary for the most effective impact of vitamin D on human physiology. The conversion of vitamin D (cholecalciferol) into active 25-OH vitamin D includes many cofactors, such as magnesium, biotin, pantethine, calcium, and boron, which are all included in the Ultra-D Complex™formula. Along with vitamin D, these cofactors support the immune system both through their own properties and by strengthening the physiological effects of vitamin D. Calcium and magnesium are of importance in intracellular metabolic functions regulated mainly via hormonal signals.
Magnesium, a predominantly intracellular ion, is involved in modulating cellular events during inflammation.57,58 Magnesium deficiency may lead to peripheral resistance to vitamin D.59 Vitamin A has an important role in the immune system and is necessary for cytokine and immune health. 60,61,62 Vitamin B6 has synergistic beneficial effects on the immune system and sugar metabolism via different pathways. Studies show that a vitamin B6 deficiency can decrease antibody production and suppress the immune response. B6 participates in the maintenance of glutathione status (as a cofactor for glutathione reductase). It has been shown that a B6 deficiency can reduce cell numbers in lymphoid tissues and cause functional abnormalities in the cell-mediated immune response. 63,64
Vitamin B6 is important in hemoglobin synthesis and increases the amount of oxygen carried by hemoglobin.64 Vitamin B6 also participates in sugar metabolism and helps maintain blood sugar within a normal range.65,66 The glyco-modulating effects of vitamin D and vitamin B6 are consistent with the lipid-modulating effects of biotin and pantethine to support glycemic balance. 67
EPA and DHA support healthy inflammatory activities by their response to proinflammatory substances, such as PGE2, LTB4, TNF-alpha, IL-1, and lipooxigenase (LOX).
Ultra-D Complex™ also provides genistein and carnosic acid to support vitamin D utilization and metabolism. Genistein can optimize the 1,25-hydroxyvitamin D3 synthesis and therefore promote increased utilization of vitamin D into an active form.1Carnosic acid from rosemary leaf extract has demonstrated the ability to potentiate the effects of vitamin D.2